Muholi's work explicitly challenges and responds to this dominant narrative by giving visibility and agency to marginalized communities, particularly Black LGBTQIA+ individuals in South Africa. Through their photography and activism, Muholi addresses issues of representation, discrimination, and erasure faced by these communities. They confront the prevalent narrative that often excludes or misrepresents their lived experiences.

Muholi's photography series featuring intimate and empowering portraits of Black lesbian, gay, bisexual, transgender, and intersex individuals disrupts the dominant narrative that often neglects or distorts their identities. By showcasing the beauty and resilience of their subjects, Muholi challenges stereotypes and confronts the erasure of their existence within mainstream representations.

Muholi challenges the dominant narrative by pushing for greater inclusion, acceptance, and rights for Black LGBTQIA+ individuals. Their efforts aim to disrupt the status quo and promote a more equitable and respectful portrayal of marginalized communities.