Chapter 4 explores how plants have been used as symbols of oppression, resilience, and liberation in African history and culture. The chapter highlights the historical and ongoing exploitation of African plant resources by colonial powers and multinational corporations, which has led to the marginalization and disempowerment of local communities. It also discusses how certain plants have been used as tools of resistance and liberation by African societies, reclaiming their agency and knowledge systems. The chapter connects the experiences of Africans in the continent and the diaspora, emphasizing the importance of solidarity and collaboration in confronting the challenges of science, technology, and innovation in Africa. It calls for a decolonization of knowledge systems and a reimagining of a more inclusive and equitable approach to science and technology in Africa. Overall, the chapter offers a thought-provoking reflection on the complex relationships between plants, power, and liberation in the African context, urging for a reevaluation of traditional narratives and a more holistic approach to science, technology, and society in Africa.